Chemical Constituents of Zygophyllum eurypterum

This book is divided into two sections; sections A and B. Section A describes the isolation and structure elucidation of seven known compounds [1-7] i.e. stigmasterol (1), -sitosterol (2), -sitosterol glucoside (3), oleanolic acid (4), harmine (5), 7,3',4'-trimethoxyflavone (6), and 5-methylflavanone (7). Compounds [5-7] were for the first time reported from this plant. Section B describes the synthesis of 2, 4, 6-trichlorophenylhydrazones and 6-nitrobenzimidazole derivatives. These synthesized compounds were also biological screened for their glycation of protein, -chymotrypsin, carbonic anhydrase, urease, antioxidant (DPPH and superoxide anion scavenging assays) and phosphodiesterase activities. Interestingly, most of these synthesized compounds showed excellent medicinal activities.

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Ph.D. (Organic Chemistry)