Chemical permeation enhancers in transdermal drug delivery system

Skin permeation enhancement technology is a rapidly developing field which would significantly increase the number of drugs suitable for transdermal drug delivery, with the result that skin will become one of the major routes of drug administration in the next decade. Research in this area has proved the usefulness of physical and chemical penetration enhancers in the enhancement of drug permeation through skin. The chemical penetration enhancement methods discussed in this review are promising. Focus should be on skin irritation, with a view to selecting penetration enhancers which possess optimum enhancement effects with minimal skin irritation.

Autorentext

Dhirendra C. Patel, Master of Pharmacy, Pharmaceutics at S.K. Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, Mehsana, Gujarat, India. Published Four International Review articles. Presented various posters. Attended state level conference. Participated in Industrial Problem Solving Ability.