Chronopharmacology in Hypertension

Chronopharmacology in hypertension management aids clinical decision making on the best administration times of antihypertensive drugs to achieve optimum circadian blood pressure (BP) control. The aims of the study were to test the effect on 24-hour BP profile of valsartan and amlodipine; to compare the effects of morning versus evening dosing on circadian BP and to compare the effects of valsartan and amlodipine between males and females. Patients suffering from essential hypertension who were prescribed once daily valsartan or once daily amlodipine participated in the study. Recruited patients had their 24h BP profiles measured using an ambulatory blood pressure monitor (ABPM).

Autorentext

Le Dr Sephorah Falzon a obtenu son doctorat à l'université de Malte en collaboration avec l'université de l'Illinois Chicago en 2018. Elle croit fermement que les pharmaciens, en collaboration avec les cliniciens, devraient jouer un rôle actif en ce qui concerne la prise de décision clinique en termes de pharmacothérapie basée sur les besoins individuels des patients.