Circulating Nucleic Acids in Plasma and Serum

This book provides an introduction to the use of circulating nucleic acids in body fluids in clinical diagnosis. It details the latest developments in the isolation of the nucleic acid fragments and their analysis, and identifies new and more reliable markers.

DNA and RNA fractions have been isolated from the whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and clinical patients. Recent developments are presented concerning the isolation, quantification and analysis of these molecules and their use in the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis.

Introduction to the use of circulating nucleic acids in body fluids in clinical diagnosis. Latest developments in the isolation of the nucleic acid fragments and their analysis. Identification of new and more reliable markers for the early diagnosis and prognosis of clinical disorders and their treatment.

Klappentext
DNA and RNA fractions have been isolated from a variety of sources including: whole blood, serum, plasma, the surface of blood cells, urine, saliva and spinal fluid from both healthy individuals and patients. The ability to isolate, quantify, and analyze these molecules has led to the identification of specific nucleic acid fragments related to a variety of clinical disorders thereby permitting their early diagnosis and prognosis. This volume encompasses the proceedings of the 6th international conference on circulating nucleic acids in plasma and serum held from the 9th to the 11th of November 2009 in Hong Kong. The topics that are covered in these proceedings include: - Nucleic Acids in Oncology - Nucleic Acids in Foetal Medicine - The Biology of CNAPS - New Technologies for CNAPS - Other Clinical Exploitation of CNAPS