Clinical Profile of Hemophilia patients of Upper Assam

All patients who were admitted in the Department of Medicine and Pediatrics with Hemophilia were included in the study. A total of 79 hemophilia patients were studied with 94.9% men and 4% women; 74.7% were below the age of 20 years and 78.5% were known hemophilia patients, whereas 21.5% were newly diagnosed; 64.6% patients had a definite family history; 79.7% were factor VIII deficient and 20.3% were factor IX deficient; 47 (74.6%) patients had severe factor VIII deficiency, 12 (19%) patients had moderate factor VIII deficiency and 4 (6.4%) patients had mild factor VIII deficiency; 11 (68.7%) patients had severe factor IX deficiency. Out of the 57 patients who presented with joint bleed 38 (67%) had knee joint involvement, 16 (28%) had ankle joint involvement, 13 (22.8%) had wrist involvement, 8 (14%) had elbow involvement and 3 (5.3%) had shoulder joint bleed. Out of the 19 cases of intramuscular bleed, 13 (68.4%) patients had psoas bleed; 43 (75.4%) patients had multiple joint involvement; 7(12.3%) patients both joint bleed and intramuscular bleed; 68.4% patients had joint deformity.Most of our patients would benefit from prophylactic treatment with regular factor replacement.

Autorentext
The Author is presently working as Assistant Professor of Medicine in Assam Medical College and Hospital. He also runs the Hemophilia Clinic in the same institute. He has several national and international publications in the field of Internal Medicine. His field of interest includes diabetes, hemophilia and bleeding disorders, mushroom poisoning.