Clinical Significance of C-reactive Protein

This book explores the latest developments in the field the acute phase protein (APP), C-reactive protein or CRP in different diseases, highlighting the structural and functional aspects of CRP in disease biology.

Divided into 5 sections, the book examines important topics such as the role of CRP in neurodegenerative, cardiac and parasitic diseases, as well as in cancer and inflammatory bowel disease, and the expression of CRP in pediatric respiratory diseases. In addition it discusses the clinical role of CRP in diagnostics and therapeutics, sepsis, ICU and ITU patients, and also as a primary marker for inflammation. Given its scope, this book will appeal to scholars in various fields of medicine and biology.

Examines the structure-function interrelationships of different isoforms of CRP in various diseases and its relevance in clinical biology Explores the functional role of CRP in animals and its implications in veterinary science Discusses the epidemiology, disease biology, pathogenesis and management of conditions like neurodegenerative diseases, inflammatory bowel disease, myocardial infarction, acute appendicitis, pediatric respiratory diseases, cancer, leishmaniasis and sepsis Describes the role of CRP as a disease marker

Autorentext

Dr. Waliza Ansar holds a Bachelor's degree in Zoology (Honors) with Chemistry and Botany and a Master's degree in Zoology from Calcutta University. She was awarded the National Scholarship in 1994. She was awarded her Ph.D. degree (2009) from CSIR- Indian Institute of Chemical Biology, Kolkata, Govt of India, after qualifying for the State Level Eligibility Test (SLET) and National Eligibility Test (NET) conducted by the Ministry of CSIR-HRDG, Govt of India . In her Ph.D work, she demonstrated various biological roles of CRP in malaria, leishmaniasis and tuberculosis. She also completed three years of postdoctoral research at CSIR-IICB, India. She has worked as a lecturer (2002-2003) in Zoology, and is currently an Assistant Professor of Zoology) at Behala College, Kolkata, where she was the Head of the department of Zoology from 2015-2017. She has also worked at Asutosh College, Kolkata as a lecturer in Environmental Science and Zoology. She has conducted researchon dipteran flies, and has published papers on CRP and therapeutic applications of monoclonal antibodies in journals such as Glycoconjugate, Cellular Physiology and Biochemistry, Immunology research, the Indian Journal of Clinical Medicine, and Journal of Stem Cells. She has also published a book chapter on nanomedicine, and a book on C-reactive protein. She has presented her work at various international and national symposiums.
Dr. Shyamasree Ghosh is currently a Scientific Officer (F) at the School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhubaneswar. She graduated from the Presidency College Kolkata in 1998 with Hons in Zoology with Chemistry and Physiology and was awarded a prestigious National Scholarship from the Govt. of India. She received her postgraduate degree in Biotechnology from Calcutta University, ranking second at the University in the year 2000. She completed her Ph.D. the field of childhoodacute lymphoblastic leukemia (ALL) at the Indian Institute of Chemical Biology, under CSIR, Kolkata, after qualifying for the National Eligibility Test conducted by the Ministry of HRD, Govt of India. Her work was accepted in various national and international journals of repute and is cited by the young researchers worldwide. She worked in the field of stem cells and nanotechnology in her post-doctoral Research. Later she joined as a faculty in post graduate college affiliated to Bangalore University. She has worked and published in Computational Immunology and Machine Learning. She has authored several publications that include books from international publishers of repute including Springer, Elsevier, CRC Press, De Gryter and encyclopedia chapters.

Inhalt

Chapter 1. Multiple Faces of C-Reactive ProteinStructure Function Relationships.- Chapter 2. C-Reactive Protein and Neurodegenerative Diseases.- Chapter 3. C-Reactive Protein in Inflammatory Bowel Disease.- Chapter 4. Study and Correlation of CRP and markers of Oxidative stress in Acute Myocardial Infarction.- Chapter 5. Role of CRP in Monitoring of Acute Pancreatitis.- Chapter 6. Role of SNP in CRP and Biology of Cancer.- Chapter 7. Role of C-Reactive Protein in Tropical Infectious Diseases .- Chapter 8. Acute Respiratory ailments in Paediatric Age Group and Role of CRP in Diagnosis and Management.- Chapter 9. Role of CRP in Sepsis: Severity and Outcome.- Chapter 10. C-Reactive Protein: Is Early Prognostic Marker?

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