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Coagulation
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Details
Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis the cessation of blood loss from a damaged vessel, wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding hemorrhage or clotting thrombosis. Coagulation is highly conserved throughout biology; in all mammals, coagulation involves both a cellular platelet and a protein coagulation factor component. The system in humans has been the most extensively researched and, therefore, the best-understood. Coagulation begins almost instantly after an injury to the blood vessel has damaged the endothelium lining of the vessel, this releases phospholipid components called tissue factor and fibrinogen that initiate a chain reaction. Platelets immediately form a plug at the site of injury; this is called primary hemostasis. Secondary hemostasis occurs simultaneously: Proteins in the blood plasma, called coagulation factors or clotting factors, respond in a complex cascade to form fibrin strands, which strengthen the platelet plug.
Weitere Informationen
- Allgemeine Informationen
- GTIN 09786130271558
- Editor Frederic P. Miller, Agnes F. Vandome, John McBrewster
- Sprache Englisch
- Größe H220mm x B150mm x T7mm
- Jahr 2009
- EAN 9786130271558
- Format Fachbuch
- ISBN 978-613-0-27155-8
- Titel Coagulation
- Untertitel Coagulation (disambiguation), Blood, Thrombus, Hemostasis, Blood Vessel, Platelet, Fibrin, Bleeding, Thrombosis, Conservation (genetics), Mammal
- Gewicht 189g
- Herausgeber Alphascript Publishing
- Anzahl Seiten 116
- Genre Biologie
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