Cochlear Mechanics

As the field of cochlear mechanics grows in sophistication, it is clear that linear systems analysis inadequately interprets the biophysics of the cochlea. This book presents a useful and more mathematically justified approach, illuminated with clear examples.

The field of cochlear mechanics has received an increasing interest over the last few decades. In the majority of these studies the researchers use linear systems analysis or linear approximations of the nonlinear (NL) systems. Even though it has been clear that the intact cochlea operates nonlinearly, lack of tools for proper nonlinear analysis, and widely available tools for linear analysis still lead to inefficient and possibly incorrect interpretation of the biophysics of the cochlea. An example is the presumption that a change in cochlear stiffness at hair cell level must account for the observed change in tuning (or frequency mapping) due to prestin application. Hypotheses like this need to be addressed in a tutorial that is lucid enough to analyze and explain basic differences.

Cochlear Mechanics presents a useful and mathematically justified/justifiable approach in the main part of the text, an approach that will be elucidated with clear examples. The book will be useful to scientists in auditory neuroscience, as well as graduate students in biophysics/biomedical engineering.

Addresses and explains basic differences between linear and nonlinear cochleae Provides a well-justified mathematical approach, with lucid examples Useful to both researchers in auditory neuroscience and students of biophysics and biomedical engineering Includes supplementary material: sn.pub/extras

Klappentext

The field of cochlear mechanics has received increasing interest over the last few decades. In the majority of these studies, researchers use linear systems analysis or linear approximations of the nonlinear (NL) systems. Even though it has been clear that the intact cochlea operates nonlinearly, lack of tools for proper nonlinear analysis, and widely available tools for linear analysis still lead to inefficient and possibly incorrect interpretation of the biophysics of the cochlea. An example is the presumption that a change in cochlear stiffness at hair cell level must account for the observed change in tuning (or frequency mapping) due to prestin application. Hypotheses like this need to be addressed in a tutorial that is lucid enough to analyze and explain basic differences.

Cochlear Mechanics presents a useful and mathematically justified/justifiable approach in the main part of the text, an approach that will be elucidated with clear examples. The book will be useful to scientists in auditory neuroscience, as well as graduate students in biophysics/biomedical engineering.

Inhalt
Part I Anatomy and Function of the Linear Cochlea.- 1 Historical Introduction.- 2 Developments from 1950 to 1980.- 3 Emerging Cochlear Mechanics.- Part II Anatomy and Function of the Nonlinear Cochlea.- 4 Nonlinear Auditory Phenomena (I) knowledge around 1980.- 5 Modeling the Nonlinear Cochlea.- Part III Results and Open Issues.- 6 Results.- 7 Applications and perspective.- Part IV Appendices.- Index