Construction and Functionalization of Heterocycles by Electrochemistry

This book highlights a selection of recent electrochemical approaches to synthesize heterocyclic compounds. Electrochemistry has recently re-emerged as a prevalent technique to promote synthetic organic reactions. This renewed interest arises from its sustainability as well as its ability to engage compounds in unique ways that complement conventional chemical reagents. In the context of heterocyclic synthesis, electrochemistry enables the annulation of simple precursors and the direct functionalization and elaboration of heterocycles, which are the focus of this volume. The primary target audience includes synthetic chemists at all levels of industry and academia.

Presents novel heteroannulation strategies Elaboration of unfunctionalized heterocycles Contributions from leading experts in the field

Autorentext

Eric was born and raised in Ontario, Canada. He graduated from Harvey Mudd College in Claremont, CA, USA in 2010 with a BSc in Chemistry, and completed a PhD at Columbia University in New York, NY, USA in 2015 studying synthetic applications of aromatic ions with Tristan Lambert. He finished his training with David MacMillan at Princeton University (Princeton, NJ, USA) as an NIH postdoctoral fellow developing new light-promoted asymmetric transformations. Eric began his independent career at Penn State University in 2019, where his group develops new catalytic approaches to organic synthesis using unique proton- and/or electron-transfer strategies.

Inhalt

Construction and derivatization of indole derivatives under electrochemical conditions.- Construction and Functionalization of heterocycles via electrochemical C-H functionalization.- Recent progress in electro-oxidative cross-coupling and annulation.- Electrochemical heterocyclic ring-forming reactions by making CN and NN bonds.- Electrochemical (hetero)spirocyclization reactions.- Electrochemical Synthesis and Functionalization of N- and S-heterocycles.- Electrochemical annulation and functionalization of multi-nitrogen-containing heteroaromatics.