Current Challenges on Large Supramolecular Assemblies

There have been several recent breakthroughs in the supramolecular domain: larger molecular components are being synthesised; 2D layers involving multiple recognition sites; crystals with intricate building blocks are being designed; more components are being used in assembly and self-assembly `algorithms' (some having molecular weights as high as 15,000); and there is an increasing versatility in applications.
The difficulty in characterising and obtaining structural information on such large assemblies has increased to such a level that no single technique is now adequate. Various methods have now been upgraded and are being combined: X-ray diffraction (structures with hundreds of independent atoms), NMR, AFM/STM (manipulation of a single molecule), FAB/MS, time-resolved techniques up to the picosecond range, new computational approaches, and others.
The present book sheds light on the most recent developments in both the synthesis of novel assemblies and on current methods for their characterisation.

Inhalt

Preface. Quantum Chrystallography: Features and Applications; J. Karle, et al. Large Molecular Assemblies Held Together by Non-Covalent Bonds; J.L. Atwood, et al. Synthetic Supramolecular Chemistry; S.J. Cantrill, et al. Beyond Supramolecular Chemistry: Supramolecular and Übersupramolecular Aspects of Chemical Structure and Reactivity: Static and Oscillating Electric and Magnetic Fields, Coherence, and Cooperativity; N.J. Turro. Non-Covalent Synthesis and Characterization of Large Supramolecular Assemblies; D.N. Reinhoudt, et al. Self-Assembling Structures Based on Hydrogen Bonding Subunits; A. Zafar, A.D. Hamilton. Hydrogen Bonds in Organised Monolayers; D. Möbius, et al. Supramolecular Architectures on Liquid Surfaces. From 2-D Assemblies to 3-D Crystals; I. Weissbuch, et al. Supramolecular Synthesis of Organic and Metal-Organic Laminates with Affinity for Aromatic Guests: Hydrophobic Clay Mimics; K. Biradha, et al. `Crystal Engineering' with Two-Dimensional Hydrogen Bonding Networks; J.A. Swift, et al. Recognition of Convex Fullerene Molecules by Concave Complexing Agents. Structure and Reactivity; H.B. Bürgi. The Structure of Solvates in the Solid State-Model Systems for Heteromolecular Association? J. Lipkowski, et al. The Role of Charge Assisted C-Hdelta+-Odelta- and C-Hdelta+-Fdelta- Hydrogen Bonds in Organometallic Crystals; D. Braga, F. Grepioni. Weak Hydrogen Bonds in Supramolecular Synthesis; A. Nangia, G.R. Desiraju. Molecular Tectonics: An Approach to Organic Networks; M.W. Hosseini. MD Simulations on Ions and Ionophores at a Liquid-Liquid Interface: From Adsorption to Recognition; F. Berny, et al. Self-Organization in Molecular Crystals, Liquids and Solutions: Computer Studies; A. Gavezotti, G. Filippini. Gas Hydrates as Self-Assembled Templated Lattices. Towards Time-Resolved Studies of Clathrate Hydrate Formation; J.A. Ripmeester, et al. Study by Electrospray Mass Spectrometry of Large Dendritic Supramolecular Complexes; E. Leize, et al. Advanced Crystallographic Methods: Experimental Electron Densities and the Study of Excited State Structure; P. Coppens. Time Resolved X-Ray Diffraction in Solids and Liquids; I.V. Tomov, et al. Single Molecule Force Spectroscopy with Individual Proteins; J.M. Fernandez, et al. Crystal Solving Procedures Applied to Peptides, Foldamers and Channel Forming Adamantyl/Peptide Hybrid Macrocycles; I.L. Karle. Tetracycline Respressor Acts as a Molecular Switch Regulated by Tetracycline Binding; W. Hinrichs, et al. Esterolytic Catalytic Antibodies; B.S. Green, M. Knossow. Weak Hydrogen Bonding in Cyclodextrin Complex Stabilisation; Th. Steiner, W. Saenger. Cyclodextrins: Towards Large Assemblies for Efficient Slow Release Devices; G. Tsoucaris, N. Rysanek. Influence of the Guest on the Packing of Dimeric &bgr;-Cyclodextrin Complexes; I.M. Mavridis. Semiconductor Nanocrystal Colloids; A.P. Alivisatos. Perspectives in Supramolecular Chemistry: From Molecular Recognition towards Self-Organization; J.-M. Lehn. Index.