Cutoff value of Glucose Challenge Test for Screening GDM

This study aimed to investigate the cut-off value of glucose challenge test (GCT) for screening Gestational Diabetes Mellitus (GDM) in a Bangladeshi population. A total of 224 Bangladeshi pregnant women who underwent a GCT were prospectively investigated. GCT was performed between 24 to 28 weeks of gestation. Women demonstrating GCT exceeding 130 mg/dl (7.2mmol/l) received a 75 g, 2 hr oral glucose tolerance test to determine whether or not they had GDM. Twenty three (10.3%) women were diagnosed to have GDM. The receiver-operator characteristics curve identified a GCT finding above 174 mg/dl as the cut-off value for detecting GDM, which showed sensitivity, specificity, PPV and NPV of 35%, 90%, 80% and 68% respectively. Based on PPV and NPV, our data suggest that 1 hr-50g GCT is a feasible and acceptable screening test and a cut-off value of 174 mg/dl, as the post-challenge serum glucose, may be appropriate for screening GDM in Bangladeshi population by this test.

Autorentext

Presently a Lecturer in the Dept of Bio-statistics in the Bangladesh Institute of Health Sciences, Bangladesh. She has accomplished M.Sc on Nutrition from the University of Dhaka and also MPH degree from the AIUB, Bangladesh. Her main research interest includes nutritional and epidemiological studies related to diabetes & other metabolic disorders.