Demethylating Agent
CHF 43.00
Auf Lager
SKU
QPBH7BK0A5K
1 Verfügbar 
Kostenloser Versand ab CHF 50
Geliefert zwischen Mi., 29.10.2025 und Do., 30.10.2025
Details
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Demethylating agents are compounds that can inhibit methylation, resulting in the expression of the previously hypermethylated silenced genes (see methylation: methylation and cancer for more detail). Cytidine analogs such as 5-azacytidine (azacitidine) and 5-azadeoxycytidine (decitabine) are the most commonly used demethylating agents . These compounds work by binding to the enzymes that catalyse the methylation reaction, DNA methyltransferases; and titrate out these enzymes. Both compounds have been approved in the treatment of Myelodysplastic syndrome (MDS) by Food and Drug Administration (FDA) in United States. Azacitidine and decitabine are marketed as Vidaza and Dacogen respectively. Azacitidine is the first drug to be approved by FDA for treating MDS and has been given orphan drug status. Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells.
30 Tage Rückgaberecht
GarantieWeitere Informationen
- Allgemeine Informationen
- GTIN 09786137769379
- Editor Christabel Donatienne Ruby
- Sprache Englisch
- Auflage Aufl.
- Genre Chemie
- Größe H229mm x B152mm x T6mm
- Jahr 2011
- EAN 9786137769379
- Format Kartonierter Einband (Kt)
- ISBN 978-613-7-76937-9
- Titel Demethylating Agent
- Untertitel Chemical compound, Methylation, Gene
- Gewicht 150g
- Herausgeber FIDEL
- Anzahl Seiten 96
Bewertungen
Schreiben Sie eine Bewertung
