Dermatopharmacology of Topical Preparations

The concept of this book is within the frame of dermatological product development as a prerequisits for clinical and registration of a given topical preparation. Additionally, efficacy claims for cosmetics must now be supported, and the book will also consider this aspect of formulation development.

Focus on experimental models (in vitro and in vivo, in animals and humans) used for screening, development of dermatological and cosmetic formulations Critical overview and practical description of the experimental models including their possibilities and limits Rapid but founded approach to questions arising at the beginning or during the development of a particular topical product Includes supplementary material: sn.pub/extras

Inhalt
General.- 2 The Vehicle: The Pharmaceutical Carrier of Dermatological Agents.- 3 The Absolute Fundamentals of Transdermal Permeation (Drug Delivery for Dummies).- 4 Basics (Guidelines) on Cell Culture Testing for Topical Dermatological Drugs/Products and Cosmetics With Regard to Efficacy and Safety of the Preparations.- 5 Guidelines and Methods on Safety Testing for Dermatics and Cosmetics.- 6 Basics on Clinical Safety Testing.- Projects.- 7 Antimicrobials.- 8 Topical Antifungal Agents.- 9 Hand Disinfection and Antiseptic of Skin, Mucous Membranes, and Wounds.- 10 Antivirals.- 11 Dermatopharmacology of Antiparasitics and Insect Repellents.- 12 Antiphlogistics (Dermocorticoids and topical immunomodulators).- 13 Antiseborrheics.- 14a Principle of Drug Treatments for Itch.- 14b Methodological Approaches for Testing Anti-Itch and Related Substances.- 15 Hair: Scalp Hair Growth Evaluation Methods.- 16 Keratolytics.- 17 Dermatopharmacology of Topical Anti-Fungal Preparations in Nail Tissue.- 18 Skin Care/Detergents.- 19 Skin Hydration.- 20 Efficacy of Skin Care Products and Different Mixtures of Lipids on Barrier Function.- 21 Project Sunscreen Protection.- 22 Photoaging - Retinoids, Alpha Hydroxy Acids, and Antioxidants.- 23 Antiperspirants.- 24 Wound Healingo.- 25 Marketing of Pharmaceutical Products.