Design, Synthesis, Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica-Based Drug Delivery Nanosystems

This thesis reports on essential advances in the design, synthesis and biomedical applications of multifunctional Mesoporous Silica Nanoparticles (MSNs). It provides several examples of multifunctional MSN-based drug delivery nanosystems and demonstrates successful synergistic cancer therapies combining MSNs and high-intensity focused ultrasound. The book will especially be of interest to researchers and graduate students in the fields of biomaterials, biology, chemistry, medicine and the life sciences who are working to develop new methods and technologies to combat cancer.

Nominated as an outstanding PhD thesis by the University of Chinese Academy of Sciences, China Presents a systematic study on the elaborate design, controlled synthesis, biomedical applications and biological effects of mesoporous silica nanoparticles (MSNs) Demonstrates successful examples of MSN-based drug delivery nanosystems for cancer diagnosis and therapy Includes supplementary material: sn.pub/extras

Inhalt
Research Background.- Synthesis of Hollow Mesoporous Silica Nanoparticles by Silica-Etching Chemistry for Biomedical Applications.- Multifunctional Mesoporous Silica Nanoparticles for Theranostics of Cancer.- Hollow Mesoporous Silica Nanoparticles for Ultrasound-Based Cancer Diagnosis and Therapy.- Summary and outlook.