Diabetes and Kidney Disease

Diabetes and Kidney Disease reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are covered, as well as an overview to the novel approaches being designed by leading researchers in the field.A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

Emphasis on a practical clinical approach with the aim of providing a convenient reference source to the general clinicians involved in the management of patients with diabetes Readers will benefit from a summary of current clinical and basic research relevant to clinical practice and understanding the pathophysiology of end-organ damage in diabetic populations A chapter is devoted to research on the future directions to prevent and or even reverse diabetic kidney and other end-organ involvement Includes supplementary material: sn.pub/extras

Autorentext
EDGAR V. LERMA, MD, FACP, FASN, FAHA, FASH, FNLA, FNKF Clinical Associate Professor of Medicine Section of Nephrology Department of Medicine University of Illinois at Chicago College of Medicine/ Associates in Nephrology, S.C.

Klappentext

Diabetes and Kidney Disease reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features, and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are covered, as well as an overview to the novel approaches being designed by leading researchers in the field.

A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

Inhalt
Background-History Part I: Natural Course, Pathogenesis, Morphology and Genetics 1. Diabetic NephropathyScope of the problem (Epidemiology, US, Japan, Europe, Obesity (Metabolic Syndrome) Geriatrics 2. Natural Course (Stages/Evidence Based Discussion) 3. Pathogenesis: Biochemical and functional alterations involving the GBM and mesangium 4. Pathogenesis: Hemodynamic alterations/renin angiotensin system 5. Renal structural damage in type 1 and type 2 DM 6. Diabetes in children and adolescents 7. Genetic markers and predictors of DN Part II: Clinical Presentation and Associated Disorders 8. Screening and early diagnosis (E. Cohen Milwaukee) 9. Differential diagnosis of proteinuria in DM (A. Reddi, NJ Med Sch) 10. Hypertension in DM 11. Cardiovascular Disease (L. Hamm, Tulane) 12. Lipid disorders 13. Eye complications in DN (Z. Karcioglu, U. Virginia) 14. Pregnancy and DN (K. KraneTulane) 15. Transplantation: Kidney, Kidney-Pancreas (R. Zhang) Part III: Treatment and Prognosis 16. Glycemic control 17. BP control in hypertensive diabetics with proteinuria 18. Early antihypertensive treatment in early stages of DN 19. Lifestyle modifications 20. Novel treatments (stem cells, islet cell transplants, gene transfer, etc.)