Digital Human Modeling and Medicine

Digital Human Modeling and Medicine: The Digital Twin explores the body of knowledge and state-of-the-art in Digital Human Modeling (DHM) and its applications in medicine. DHM is the science of representing humans with their physical properties, characteristics and behaviors in computerized, virtual models. These models can be used standalone or integrated with other computerized object design systems to both design or study designs of medical devices or medical device products and their relationship with humans. They serve as fast and cost-efficient computer-based tools for the assessment of human functional systems and human-system interaction.

This book provides an industry first introductory and practitioner focused overview of human simulation tools, with detailed chapters describing body functional elements and organs, organ interactions and fields of application. Thus, DHM tools and a specific scientific/practical problem - functional study of the human body - are linked in a coherent framework. Eventually the book shows how DHM interfaces with common physical devices in medical practice, answering to a gap in literature and a common practitioner question. Case studies provide the applied knowledge for practitioners to make informed decisions.

Autorentext
Gunther Paul is an Ergonomist and James Cook University Principal Research Fellow for Occupational Health and Safety at the Australian Institute for Tropical Health and Medicine (AITHM), and the Mackay Institute for Research and Innovation (MIRI). He holds a PhD in Ergonomics and MPhil in Control Engineering from Darmstadt University of Technology. His research focuses on complex work system related issues, such as health systems, respiratory health, human-in-the-loop modelling, or musculoskeletal disorders. Gunther has been the Chief Investigator in 17 research projects. He is the Editor-In-Chief of the International Journal of Human Factors Modelling and Simulation, and a reviewer for over 20 international journals. He chairs the International Ergonomics Association Technical Committee on Human Simulation and Virtual Environments, and is a Member of the Queensland Government Safety Leadership at Work Expert Reference Group, Member of the Commonwealth Department of Employment Research and Evaluation Services Panel, and Member of the Panel of Assessors, Queensland Civil and Administrative Tribunal (QCAT). Gunther is also the Ambassador of the Foundation for Professional Ergonomics in Australia. He has published over 100 journal articles, books and book chapters, and has been regularly presenting and chairing sessions at International conferences over the last 25 years. In his most recent previous employments, Gunther led the Health Safety Environment Discipline in the School of Public Health and Social Work at QUT, and before that he was Director of Ergolab at UniSA. In his 10 year industrial career, he worked as Project Manager for Ford, Daimler, and Faurecia. He is a Full Associate Professor at the Mechanical Engineering Department, University of Zaragoza, Spain (25 years of teaching experience). Besides, he is a Member of the Group of Applied Mechanics and Bioengineering (AMB), the Biomedical Research Networking Center in Bioengineering, Biomaterials, and Nanomedicine (CIBER-BBN), the Aragón Institute of Engineering Research (I3A), and the European Society of Biomechanics (ESB). He received his B.Eng. in industrial engineering (1993) from Benha Higher Institute of Technology, Egypt; B.Sc. in statistical and computer science (1997) from Mansoura University, Egypt; M.Sc. degree in Engineering Mathematics (2001) from Ain Shams University, Egypt; a Diploma in Advanced Studies in Computational Fluid Mechanics (2004) from Zaragoza University, Spain; and his Ph.D. degree in Computational Fluid Mechanics (2005) from Zaragoza University, Spain. Dr. Doweidar has participated and/or directed more than 25 national and international investigation projects. In addition, he is the author and co-author of more than 110 publications in peer-reviewed articles, books, book chapters, and conferences. His investigation interests include Computational Biomechanics, Cell Simulation, Hyperelastic Materials, Large Deformations, Finite Element Method, Natural Element Method, Computational Fluid Dynamics, Error Estimation, and Adaptivity.

Klappentext
Digital Human Modeling and Medicine: The Digital Twin explores the body of knowledge and state-of-the-art in Digital Human Modeling (DHM) and its applications in medicine. DHM is the science of representing humans with their physical properties, characteristics and behaviors in computerized, virtual models. These models can be used standalone or integrated with other computerized object design systems to both design or study designs of medical devices or medical device products and their relationship with humans. They serve as fast and cost-efficient computer-based tools for the assessment of human functional systems and human-system interaction.

This book provides an industry first introductory and practitioner focused overview of human simulation tools, with detailed chapters describing body functional elements and organs, organ interactions and fields of application. Thus, DHM tools and a specific scientific/practical problem - functional study of the human body - are linked in a coherent framework. Eventually the book shows how DHM interfaces with common physical devices in medical practice, answering to a gap in literature and a common practitioner question. Case studies provide the applied knowledge for practitioners to make informed decisions.

Inhalt

1. Virtual Human Anatomy Atlases
   
   2. The Visible Human Project
   3. The Virtual Physiological Human
   4. Human Modeling Software Systems
   5. Human Modeling Hardware Systems
   6. Mandibular Biomechanics
   7. Corneal Biomechanics
   8. Biomechanics and Modeling of the Human Heart
   9. Biomechanics and Modeling of the Human Lung
   10. Biomechanics and Modeling of the Human Spine
   11. Biomechanics and Modeling of the Human Shoulder
   12. Prosthetic Modeling of the Leg
   13. Bone Tissue Remodeling of the Femur
   14. Computational Musculoskeletal Biomechanics of the Knee
   15. Biomechanics and Modeling of the Human Foot
   16. Multiphasic and Multiscale Modelling of Vascular Tissue
   17. Simulation of the Blood Flow in Body Arteries
   18. Patient-Specific Predictive Modeling
   19. Real-Time Simulation of Virtual Surgery
   20. Computational Simulation of the Cell Behavior for Tissue Regeneration
   21. Cartilage Regeneration
   22. Bone Regeneration
   23. Damage, Remodeling, and Growth of Vascular tissue
   24. Microfluidics Chips to Mimic the Cellular Microenvironment
   25. Nano-Structured Materials as a Scaffold for Tissue Regeneration
   26. Smart Materials as a Scaffold for Tissue Regeneration
   27. Synthesis of Highly Reactive Polymers for Tissue Adhesiveness
   28. Mechanical and Micro-Structural Behavior of Biomaterials and Biological Tissue
   29. 3D Remodeling and Printing of Implants