Dimedone based nucleus and its biological activities

Here's an update review of Dimedone chemistry and it's important as a starting stone to build up a large active nucleus with biologically important in the medical field. Qinazolines and Acridines with the modern multi-component synthesis methods. Biological Activities of various quinazolines, acridines and hydrazones. Molecular hybridization methods used to design biologically active non classical acridines, hydrazones and quinazolines. The plane of synthesis of a new series hexahydroquinazolinone was done by a new strategy which includes only two steps starting from simple synthons dimedone and 4-aminoacetophenone, and then multi-components reaction of the resulted enaminone with formalin and different substituted anilines to give the targeted quinazolinones through a few steps and excellent yields. and an intelligent method to synthesis of acridine and hdrazine by simple method with excellent yields.

Autorentext

Mohammed A. Hara was born in Egypt 1979, Al-Azher University (B.S. in pharmaceutical science) and the University of Suez Canal (Master degree in Pharmaceutical Organic Chemistry). My research interests are in synthetic organic and carbohydrate chemistry, and in functionalized carbon nano-materials.

Klappentext

Here's an update review of Dimedone chemistry and it's important as a starting stone to build up a large active nucleus with biologically important in the medical field. Qinazolines and Acridines with the modern multi-component synthesis methods. Biological Activities of various quinazolines, acridines and hydrazones. Molecular hybridization methods used to design biologically active non classical acridines, hydrazones and quinazolines. The plane of synthesis of a new series hexahydroquinazolinone was done by a new strategy which includes only two steps starting from simple synthons dimedone and 4-aminoacetophenone, and then multi-components reaction of the resulted enaminone with formalin and different substituted anilines to give the targeted quinazolinones through a few steps and excellent yields. and an intelligent method to synthesis of acridine and hdrazine by simple method with excellent yields.