DNA and Aptamer Biosensors

In the last years, DNA arrays have attracted
increasing attention among medical diagnosis and
analytical chemists. The broad range of application
that has been found for DNA arrays makes them an
important analytical tool.
The main goal of this book is to broadly review the
emerging technology of oligonucleotide based
biosensors for DNA and protein detection, devoting
special attention in target label free
electrochemical biosensors. The first two chapters
explore the technology behind oligonucleotide and
aptamer based biosensors and review the state of the
art of these devices. In next chapters, emphasis is
laid on the experimental development of biosensors,
ranging from bio-self assembled surfaces modification
to arrays microfabrication and from electrochemical
detections to oligonucleotide label-conjugation.
This book provides a useful tool for study thoroughly
this emerging field, giving to the reader not only a
wide biosensors overview, but also experimental
protocols for the development of these devices. This
book should be specially useful for researchers in
biosensors, electrochemistry detection and
bio-surface modification or anyone else interested on
this topic.

Autorentext

Dr. Mònica Mir, Chemist: Researcher and project manager in theBioengineering and Bioelectrochemistry Group in the UniversityRovira i Virgili, where she received her PhD in Biotechnology.She was postdoctoral fellowship in Max Planck Institute withProf. Knoll. Nowadays, she joins the Institute for Bioengineeringof Catalonia with Prof. Samitier.

Klappentext

In the last years, DNA arrays have attractedincreasing attention among medical diagnosis andanalytical chemists. The broad range of applicationthat has been found for DNA arrays makes them animportant analytical tool. The main goal of this book is to broadly review theemerging technology of oligonucleotide basedbiosensors for DNA and protein detection, devotingspecial attention in target label freeelectrochemical biosensors. The first two chaptersexplore the technology behind oligonucleotide andaptamer based biosensors and review the state of theart of these devices. In next chapters, emphasis islaid on the experimental development of biosensors,ranging from bio-self assembled surfaces modificationto arrays microfabrication and from electrochemicaldetections to oligonucleotide label-conjugation.This book provides a useful tool for study thoroughlythis emerging field, giving to the reader not only awide biosensors overview, but also experimentalprotocols for the development of these devices. Thisbook should be specially useful for researchers inbiosensors, electrochemistry detection andbio-surface modification or anyone else interested onthis topic.