Dopamine Signaling Importance in Human body

Dopamine, also called hydroxytyramine, a nitrogen-containing organic compound formed as an intermediate compound from dihydroxyphenylalanine (dopa) during the metabolism of the amino acid tyrosine. It is the precursor of the hormones epinephrine and norepinephrine.Dopamine is a neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dysfunction of the dopamine system has been implicated in different nervous system diseases. The level of dopamine transmission increases in response to any type of reward and by a large number of strongly additive drugs. The role of dopamine dysfunction as a consequence of oxidative stress is involved in health and disease.

Autorentext

Asst. Prof. Wael Mahmoud Aboulthana, Biochemistry Department, Biotechnology Research Institute, National Research Centre. Asst. Prof. Noha El-Sayed Ibrahim, Department of Microbial Biotechnology, National Research Centre. Dr. Amal Gouda Hussien, Biochemistry Department, Biotechnology Research Institute, National Research Centre.