Epigenetic Predictors of chemosensitivity of Colorectal Cancer

The Epigenetic Keys to Therapeutics Effectiveness of Fluoropyrimidine Therapy in Colorectal Cancer. Global DNA methylation as 5- methyl cytosines could be considered as a prognostic determinant of treatment efficacy. The methylation and expression of cycloxygenase and fluoropyrimidine metabolizing genes exhibited a clinical significance for individualized treatment. The Molecular Follow- Up along with the Clinicopathological Follow- Up is crucial for best management of colorectal cancer.

Autorentext

Mariam A. Fouad Hafez, PhD Cancer Biology (Pharmacology and Experimental Oncology), Lecturer in Pharmacology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Egypt.