Evaluation of Fast Dissolving Tablets

Gabapentin is an anti-epileptic drug used in the treatment of Epilepsy. It is a water soluble drug with bioavailability of 100% and plasma half-life 5 to 7 hrs. Gabapentin tablets with various superdisintegrant were developed as oral drug delivery systems to enhance safety, efficacy of the drug molecule and to achieve better patient compliance. In the present investigation, Gabapentin tablets were formulated by direct compression by incorporating various concentrations of superdisintegrant intra and extra granularly (IG and EG).

Autorentext

Dr D. Akiladevi, professeur associé, École des sciences pharmaceutiques, Vels Institute of Science, Technology and Advanced Studies, Chennai, Inde.Dr. E. Karthikeyan, professeur, Saveetha Institute of Science Technology and Advanced Studies.