Fibronectin

CHF 67.50
Auf Lager
SKU
22EETCNR8PG
Stock 1 Verfügbar
Geliefert zwischen Mo., 17.11.2025 und Di., 18.11.2025

Details

Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins. In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin and heparan sulfate proteoglycans (e.g. syndecans). Fibronectin exists as a dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms. Two types of fibronectin are present in vertebrates: soluble plasma fibronectin (formerly called "cold-insoluble globulin", or CIg) is a major protein component of blood plasma (300 g/ml) and is produced in the liver by hepatocytes. Insoluble cellular fibronectin is a major component of the extracellular matrix. It is secreted by various cells, primarily fibroblasts, as a soluble dimer and is then assembled into an insoluble matrix in a complex cell-mediated process.

Weitere Informationen

  • Allgemeine Informationen
    • GTIN 09786130602000
    • Editor Frederic P. Miller, Agnes F. Vandome, John McBrewster
    • Sprache Englisch
    • Genre Chemie
    • Größe H220mm x B150mm x T11mm
    • Jahr 2010
    • EAN 9786130602000
    • Format Fachbuch
    • ISBN 978-613-0-60200-0
    • Titel Fibronectin
    • Untertitel Molecular mass, Extracellular matrix, Glycoprotein, Cell membrane, Receptor (biochemistry), Integrin, Fibrin, Heparan sulfate, Proteoglycan, Syndecan, Dimer, Monomer, Disulfide bond
    • Gewicht 290g
    • Herausgeber Alphascript Publishing
    • Anzahl Seiten 184

Bewertungen

Schreiben Sie eine Bewertung
Nur registrierte Benutzer können Bewertungen schreiben. Bitte loggen Sie sich ein oder erstellen Sie ein Konto.
Made with ♥ in Switzerland | ©2025 Avento by Gametime AG
Gametime AG | Hohlstrasse 216 | 8004 Zürich | Schweiz | UID: CHE-112.967.470