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Fibronectin
CHF 67.50
Auf Lager
SKU
22EETCNR8PG
Geliefert zwischen Mo., 17.11.2025 und Di., 18.11.2025
Details
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins. In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin and heparan sulfate proteoglycans (e.g. syndecans). Fibronectin exists as a dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms. Two types of fibronectin are present in vertebrates: soluble plasma fibronectin (formerly called "cold-insoluble globulin", or CIg) is a major protein component of blood plasma (300 g/ml) and is produced in the liver by hepatocytes. Insoluble cellular fibronectin is a major component of the extracellular matrix. It is secreted by various cells, primarily fibroblasts, as a soluble dimer and is then assembled into an insoluble matrix in a complex cell-mediated process.
Weitere Informationen
- Allgemeine Informationen
- GTIN 09786130602000
- Editor Frederic P. Miller, Agnes F. Vandome, John McBrewster
- Sprache Englisch
- Genre Chemie
- Größe H220mm x B150mm x T11mm
- Jahr 2010
- EAN 9786130602000
- Format Fachbuch
- ISBN 978-613-0-60200-0
- Titel Fibronectin
- Untertitel Molecular mass, Extracellular matrix, Glycoprotein, Cell membrane, Receptor (biochemistry), Integrin, Fibrin, Heparan sulfate, Proteoglycan, Syndecan, Dimer, Monomer, Disulfide bond
- Gewicht 290g
- Herausgeber Alphascript Publishing
- Anzahl Seiten 184
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