Fluorinated Biomaterials

The application of supercritical carbon dioxide has
been attracting more attention in the synthesis of
biodegradable polymers. Highly pure products without
residues can be recovered after the polymerization in
supercritical carbon dioxide. In this book, the
synthesis steps of polyester-based biodegradable
polymers and the production of nanofiber scoffolds
from these polymers are reported in details.
For the synthesis of polyester-based biodegradable
polymers, three types of block fluorinated
poly(L-lactide-co- -caprolactone) are synthesized in
supercritical carbon dioxide using reactive
stabilizers including inner fluorinated segment and
polylactide or polycaprolactone side chains.
Perfluoro polyethers can be used as blood substitutes
to deliver oxygen to tissues so that these materials
are promising for biomedical applications.
For the production of nanofiber scoffolds,
electrospinning process is used to fabricate
nanofiber scaffolds from synthesized biodegradable
materials.
Material characterization is carried out by nuclear
magnetic resonance spectroscopy, differential
scanning calorimetry, gel permeation
chromatography,optical microscopy and scanning
electron microscopy.

Autorentext

Burcu Saner received a BS degree in Chemistry at MiddleEast Technical University in 2005 and a MSdegree in Materials Science and Engineering at SabanciUniversity in 2007. Mrs. Saner still continues her PhD researchat Sabanci University. Dr. Yusuf Menceloglu is currently a professorat Sabanci University in Materials Science and Engineering.

Klappentext

The application of supercritical carbon dioxide hasbeen attracting more attention in the synthesis ofbiodegradable polymers. Highly pure products withoutresidues can be recovered after the polymerization insupercritical carbon dioxide. In this book, thesynthesis steps of polyester-based biodegradablepolymers and the production of nanofiber scoffoldsfrom these polymers are reported in details.For the synthesis of polyester-based biodegradablepolymers, three types of block fluorinatedpoly(L-lactide-co-e-caprolactone) are synthesized insupercritical carbon dioxide using reactivestabilizers including inner fluorinated segment andpolylactide or polycaprolactone side chains.Perfluoro polyethers can be used as blood substitutesto deliver oxygen to tissues so that these materialsare promising for biomedical applications. For the production of nanofiber scoffolds,electrospinning process is used to fabricatenanofiber scaffolds from synthesized biodegradablematerials. Material characterization is carried out by nuclearmagnetic resonance spectroscopy, differential scanning calorimetry, gel permeationchromatography,optical microscopy and scanningelectron microscopy.