Formulation, Development, And In-vivo Studies Of Anti-hiv Vaginal Film

A tremendous development has been made in the field of controlled drug delivery system in the last few decades. The term control release has a meaning not only the scope of sustained action but also it implies a predictability and reproducibility in the drug release kinetics, which means the release of drug ingredients from the delivery system produce at a rate profile that is not only predictable kinetically, but also reproducible from one unit to another. Recently, several technical advancements have been made. The vagina is perhaps a less explored but efficient route for drug administration due to presence of dense blood vessels network and avoids liver first-pass. To date, most vaginal drug delivery systems have been formulated as conventional / traditional formulations such as gel, tablet etc. However, a clear justification subsists for providing long-term, controlled release of vaginal anti-retroviral in order to provide continuous protection against heterosexually transmitted HIV infection and to improve user compliance. The study is devoted to the development and characterization of Bio-adhesive Vaginal Film.

Autorentext

Bhargabjyoti Sahariah is currently working as Assistant Professor of pharmaceutics, Assam down town University, India. He was awarded PG in Pharmaceutics from University of North Bengal in the year 2009.He has number of publications in peered reviewed National & International Journals to his credit and attended many conferences and seminars.