Formulation evaluation of bilayer tablet of saxagliptin & repaglinide

Bilayer tablet has been made and evaluated. For various precompression and post compression parameter. Precompression parameter shows that the granules and blends of repaglinide and saxagliptin have good Carr's index and hausner's ratio indicate that both granules and blends were free flowing. The angle of repose shows that granules and blends have excellent flow and post compression parameter show that bilayer tablet have thickness hardness and weight and friability within the I. P. limit and bilayer tablet have swelling index 82% in 6 hrs and have drug release first layer of saxagliptin release 98.6% in 30 minutes and second layer repaglinide release 95.5% in 12 hrs.

Autorentext

Anjali Soni travaille actuellement comme professeur assistant au LNCP Indore. Elle a trois ans d'expérience dans le domaine universitaire, elle a obtenu un M.pharma à l'AIPER Indore et un B.pharma au BRNCOP Mandsour. Elle a publié deux articles de recherche et plusieurs sont communiqués à des revues. Elle est également membre de l'APTI.