Formulation & Development of Floating Drug Delivery System

From above experimental findings it can be concluded that: - Floating tablet of Clopidogrel Bisulphate can be formulated by effervescent technique using combination of different grades of HPMC. - The prepared floating tablets of Clopidogrel Bisulphate showed satisfactory physicochemical properties and floating behaviour. - The mechanism of drug release was found to be matrix diffusion controlled. - Formulations showed satisfactory results from Stability studies. - Further in-vivo investigations are necessary to correlate in-vitro data.

Autorentext

Pankaj Chasta, a post graduate researcher and Assistant Professor at Department of Pharmacy, Mewar University. I have completed post graduation (M.Pharma ) in Pharmaceutics from Pacific University, Udaipur, Rajasthan, India.

Klappentext

From above experimental findings it can be concluded that: Floating tablet of Clopidogrel Bisulphate can be formulated by effervescent technique using combination of different grades of HPMC. The prepared floating tablets of Clopidogrel Bisulphate showed satisfactory physicochemical properties and floating behaviour. The mechanism of drug release was found to be matrix diffusion controlled. Formulations showed satisfactory results from Stability studies. Further in-vivo investigations are necessary to correlate in-vitro data.