Fortschritte der Chemie organischer Naturstoffe

The condensed tannins (syn. polymeric proanthocyanidins) represent a major group of phenolic compounds in woody and some herbaceous plants (1-3). Their exceptional concentrations in the barks and heartwoods of a variety of tree species have resulted in their commercial extraction with the initial objective of applying the extracts in leather manufacture (4). Essentially all of their biological significance, e. g. the protection of plants from insects, diseases and herbivores, and most of the current, e. g. leather manufacture, and also most promising new uses, e. g. pharmaceuticals or wood preservatives, rest on their com plexation with other biopolymers like proteins and carbohydrates, or metal ions (5, 6). Increasing attention has thus been directed to understanding their conformation and conformational flexibility (7-20) in order to explain their biological activity and to provide a basis for further development of uses for these renewable phenolic compounds. Recent developments have also been initiated by the growing realization that the condensed tannins may additionally be credited for the profound health-beneficial properties of tea, fruit juices and red wine. This is mainly due to their in vitro radical scavenging (21) or antioxidant (22) biological properties, while the polymeric proanthocyanidins in red wine have been implicated in protection against cardiovascular disorders (23), e. g. the "French paradox" (24-26). Collectively these 'positive' characteristics of the polymeric proanthocyanidins have transformed "a relatively unattractive and therefore neglected area of study" (27) into, yet again, a fashionable research field.

Klappentext

The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.

Inhalt
Secondary Metabolites and the Control of Some Blue Stain and Decay Fungi (W. A. Ayer, L. S. Trifonov): Introduction; Blue Stain Fungi; Decay Causing Fungi; The Black Gall Effect; References.- Condensed Tannins (D. Ferreira, E. V. Brandt, J. Coetzee, E. Malan): Introduction; Formation of the Interflavanyl Bond in Oligomeric Proanthocyanidins; Cleavage of the Interflavanyl Bond in Oligomeric Proanthocyanidins; Rearrangement of the Pyran Heterocycle of Oligomeric Proanthocyanidins; Conformational Analysis of Dimeric Proanthocyanidins; Conclusion.- Constituents of //Lactarius// (Mushrooms) (W. M. Daniewski, G. Vidari): Introduction; Sesquiterpenes Isolated from //Lactarius//; Introduction to Parts 6 and 7 Velutinal Esters and Related Sesquiterpenes; Chemistry of Sesquiterpenes of //Lactarius//.- References.- Author Index.- Subject Index.