Free-Radical Synthesis and Functionalization of Heterocycles

Provides readers with an overview of free-radical chemistry as an environmentally benign synthetic strategy to access heterocycles Emphasizes the high bond forming efficiency of using radical cascade and electron-transfer processes Highlights the latest developments in use of light and metal-catalysis to trigger single electron transfer (SET) processes Covers many different examples including detailed mechanistic insights

Autorentext
Yannick Landais was born in Angers (France) in 1962. He received his PhD in chemistry from the University of Orsay (Paris XI) under the supervision of Dr. Jean-Pierre Robin. After carrying out post-doctoral studies with Prof. Ian Fleming at Cambridge University (1988-1990), he took a position of Maitre-Assistant at the University of Lausanne (1990-1997). He was then appointed at the University Bordeaux-I where he is currently Professor of organic chemistry. His research interests are in synthetic organic chemistry, asymmetric synthesis, radical chemistry, with a special emphasis on organosilicon chemistry and its applications in total synthesis of natural products. In 1997, he was awarded the Werner prize by the New Swiss Chemical Society. Between 2000 and 2005, he was a member of the Institut Universitaire de France. In 2014, he was elected as a senior Distinguished Member of the Société Chimique de France (SCF) and was awarded the SCF's Organic Chemistry Division prize the same year.He is currently President of the French-Japanese Chemical Society and is a member of the International Advisory Board of the European Journal of Organic Chemistry.

Inhalt

Photocatalyzed Formation of Heterocycles.- CH activation via radical processes using photo-excited ketones.- Free Radicals in Heterocycle Functionalization.- Heteroatom-Centred Radicals for the Synthesis of Heterocyclic Compounds.- Metal-Mediated Oxidative Radical Processes for the Synthesis of Heterocycles.- Reductive Electron Transfer in the Synthesis of Heterocycles.- Synthesis of Nitrogen-Containing Heterocycles via Imidoyl or Iminyl Radical Intermediates.- Radical cascades in the total synthesis of complex naturally occurring heterocycles.