Gene Therapy, An Issue of Hematology/Oncology Clinics of North America: Volume 31-5

This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.

Inhalt

Hematology/Oncology Clinics * Gene Therapy

• Preface: Gene Therapy

  Historical Perspective on the Current Renaissance for Hematopoietic Stem Cell Gene Therapy

  Integrating Vectors for Gene Therapy and Clonal Tracking of Engineered Hematopoiesis

  Nonintegrating Gene Therapy Vectors

  In Vivo Hematopoietic Stem Cell Transduction

  Therapeutic Gene Editing Safety and Specificity

  Gene Editing: Regulatory and Translation to Clinic

  Opening Marrow Niches in Patients Undergoing Autologous Hematopoietic Stem Cell Gene Therapy

  Gene Therapy Approaches to Immunodeficiency

  Gene Therapy Approaches to Hemoglobinopathies

  Gene Therapy for Hemophilia

  Hematopoietic Gene Therapies for Metabolic and Neurologic Diseases

  Gene Therapy Approaches to Human Immunodeficiency Virus and Other Infectious Diseases

  Hematopoietic Stem Cell Approaches to Cancer

  Gene Modified T Cell Therapies for Hematological Malignancies