Gilbert's Syndrome
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High Quality Content by WIKIPEDIA articles! Gilbert's syndrome, often shortened to GS, also called Gilbert-Meulengracht syndrome, is the most common hereditary cause of increased bilirubin and is found in up to 5% of the population (though some gastroenterologists maintain that it is closer to 10%). It has an autosomal recessive pattern of inheritance. The main symptom is otherwise harmless jaundice, which does not require treatment, caused by elevated levels of unconjugated bilirubin in the bloodstream (hyperbilirubinemia). The cause of this hyperbilirubinemia is the reduced activity of the enzyme glucuronyltransferase, which conjugates bilirubin and some other lipophilic molecules. Conjugation renders the bilirubin water-soluble, after which it is excreted in bile into the duodenum.
Weitere Informationen
- Allgemeine Informationen
- Editor Frederic P. Miller, Agnes F. Vandome, John McBrewster
- Titel Gilbert's Syndrome
- Format Kartonierter Einband
- EAN 9786131609251
- Genre Medizin
- Anzahl Seiten 72
- Herausgeber Alphascript Publishing
- GTIN 09786131609251
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