Handbook of Glycomics

Klappentext This handbook provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Zusammenfassung Offers a comprehensive overview of the field of glycomics! defined as the study of complex carbohydrates in an organism or cell ('the glycome'). This work discusses specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylation. It includes discussions of proteomics! mass spectrometry! and NMR. Inhaltsverzeichnis Introduction to Glycomics SECTION 1: Glycoconjugate Structural Analysis 1. Glycoproteomics: N-glycan Analysis 2. Glycoproteomics: O-glycan Analysis 3. Glycosaminoglycans 4. Isotopic Labeling of Glycans for Quantitative Glycomics SECTION II: Glycotranscriptomics 5. Glycotranscriptomics SECTION III: Protein-Glycan Interactions 6. Glycan Arrays 7. Chromatographic and Mass Spectrometric Techniques SECTION IV: Glycobioinformatics 8. Integration of Glycomics Knowledge and Data 9. KEGG GLYCAN for integrated analysis of pathways, genes, and glycan structures 10. European Glycomics Portal SECTION V: Glycomes 11. Glycomics of the Immune System 12. Mouse and Human 13. Drosophila 14. Malaria 15. Parasitic Worms SECTION VI: Disease Glycomes 16. Cancer Glycomics 17. An Introduction to Human Disorders of Glycosylation 18. Summary

Zusammenfassung
Offers a comprehensive overview of the field of glycomics, defined as the study of complex carbohydrates in an organism or cell ('the glycome'). This work discusses specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylation. It includes discussions of proteomics, mass spectrometry, and NMR.

Inhalt

Introduction to Glycomics

SECTION 1: Glycoconjugate Structural Analysis 1. Glycoproteomics: N-glycan Analysis 2. Glycoproteomics: O-glycan Analysis 3. Glycosaminoglycans 4. Isotopic Labeling of Glycans for Quantitative Glycomics SECTION II: Glycotranscriptomics 5. Glycotranscriptomics SECTION III: Protein-Glycan Interactions 6. Glycan Arrays 7. Chromatographic and Mass Spectrometric Techniques

SECTION IV: Glycobioinformatics

8. Integration of Glycomics Knowledge and Data

9. KEGG GLYCAN for integrated analysis of pathways, genes, and glycan structures

10. European Glycomics Portal SECTION V: Glycomes

11. Glycomics of the Immune System

12. Mouse and Human

13. Drosophila

14. Malaria

15. Parasitic Worms

    SECTION VI: Disease Glycomes

16. Cancer Glycomics

17. An Introduction to Human Disorders of Glycosylation

18. Summary