Heterocyclic Antitumor Antibiotics

Heterocyclic chemistry is the biggest branch of chemistry covering two-third of the chemical literature. Research papers in heterocyclic chemistry are published in almost all the journals of chemistry and organic chemistry in addition to five journals devoted to heterocyclic chemistry: (J.Heterocycl.Chem.; Heterocycles; Heterocycl.Commun. and Heterocyclic Compounds; Ind. J. Heterodycl. Chem.); additionally, some monographs are published in heterocyclic chemistry every year. Our review series is topic related It comprises 30-50 pages per contribution and covers the research results of the topic of the past 5-10 years. Online version available on SpringerLink.com

Zusammenfassung

From the reviews:

"Heterocyclic antitumor antibiotics represent a broad class of natural products that are of widespread interest ... . Thus, a well-written, up-to-date account of progress in the study of such compounds is expected to be well received. ... this monograph certainly has sufficient scientific value to merit inclusion in most academic libraries and in industrial laboratories concerned with antibacterial and anticancer agent discovery. Individual researchers, on the other hand, might first wish to weigh the extent to which this far-ranging collection of reviews deals sufficiently with topics of specific interest to their research groups before acquiring a personal copy." (Gary I. Dmitrienko, Journal of the American Chemical Society, Vol. 129, 2007)

Inhalt

T. Brown, H. Holt Jr., M. Lee: Synthesis of Biologically Active Heterocyclic Stilbene and Chalcone Analogs of Combretastatin.- J.T. Gupton: Pyrrole Natural Products with Antitumor Properties.- Brian E. Love: Synthesis of Carbolines Possessing Antitumor Activity.- D.P. Arya: Diazo and Diazonium DNA Cleavage Agents: Studies on Model Systems and Natural Product Mechanisms of Action.- M. Daneshtalab: Novel Synthetic Antibacterial Agents.- S.N. Maiti, R.P. Kamalesh Babu, R. Shan: Overcoming Bacterial Resistance: Role of ß-Lactamase Inhibitors.