Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of neurodegenerative disease and illustrates the involvement of human caspases, neuronal apoptosis, apoptotic pathways, genetic polymorphisms, and several other factors and underlying mechanisms in the pathology of Alzheimer's disease, Parkinson's disease, and Huntington's disease. An important focus in all chapters is the intricate mechanisms and interplay that occur during or leading to neuron death in neurodegenerative diseases, along with disease pathobiology.

Autorentext

Prof. (Dr.) Anil Gupta, (D. Sc), Ph.D., M.Sc., B.D.S B.Sc has more than 14 years of teaching experience, 7 years of postdoctoral research experience, and 8 years of PhD supervisor experience, and 25 years of clinical experience. His research interests are in distinctive fields as heavy metals contamination and quality of drinking water, predisposition of blood groups to diabetes mellitus and dyslipidemia, nutritional status of preschool children, habit of geophagia, neurodegenerative diseases, and insulin resistance. He has been an examiner to PhD scholars and dental undergraduates. He is serving as a reviewer and editorial board member in multidisciplinary journals.

Klappentext

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of neurodegenerative disease and illustrates the involvement of human caspases, neuronal apoptosis, apoptotic pathways, genetic polymorphisms, and several other factors and underlying mechanisms in the pathology of Alzheimer's disease, Parkinson's disease, and Huntington's disease. An important focus in all chapters is the intricate mechanisms and interplay that occur during or leading to neuron death in neurodegenerative diseases, along with disease pathobiology.

Inhalt

1. Neurodegenerative Diseases: Neuropathology, Genetics, and Epidemiology
   
   2. Role of Caspases, Apoptosis and Additional Factors in Pathology of Alzheimer's disease
   3. Role of Caspases and Apoptosis in Parkinson's disease
   4. Illustrated Etiopathogenesis of Huntington's Disease