Hydrolysis of Synthetic Chiral Organic Phosphoramidates

Noble chiral organic (mixed) phosphoramidates contain both C-O-P and C-N-P linkages and are found to possess great biological significance as intermediates in metabolism. Moreover, new promising phosphoramidate prodrugs have been developed recently. This book therefore, provides new milestone towards synthesis of chiral organic phosphoramidates and their hydrolytic degradation studies. The different chapters have been assigned to facilitate an easier understanding of the following titles: Introduction to the recent investigations in phosphoramidates Synthesis of chiral phosphoramidates Characterization by various spectroscopic methods. Kinetic study/in vitro hydrolytic reactivity study. With its clear and systematic presentation, this book will pave great beneficial understanding to researchers, scholars and students at large.

Autorentext

Soram Ibomcha Singh is an Assistant Professor in Engineering Chemistry. He has published research papers in National and International journals of repute in the areas of 'Phosphorus Chemistry' and 'Decontamination of Toxic Chemicals'. He obtained his Ph.D. Degree under the guidance of Dr. Shashi Prabha, Jiwaji University, Gwalior, India, in 2009.