IKK2

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Details

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. IKK- is an enzyme that serves as a protein subunit of I B kinase, which is a component of the cytokine-activated intracellular signaling pathway involved in triggering immune responses. Its activity causes activation of a transcription factor known as Nuclear Transcription factor kappa-B or NF- B. Activated IKK- phosphorylates a protein called the inhibitor of NF- B, I B (I B ), which binds NF- B to inhibit its function. Phosphorylated I B is degraded via the ubiquitination pathway, freeing NF- B, and allowing its entry into the nucleus of the cell where it activates various genes involved in inflammation and other immune responses.

Weitere Informationen

  • Allgemeine Informationen
    • GTIN 09786131269226
    • Editor Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow
    • Größe H220mm x B220mm
    • EAN 9786131269226
    • Format Fachbuch
    • Titel IKK2
    • Herausgeber Betascript Publishing
    • Anzahl Seiten 153
    • Genre Biologie

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