Imines of Gabapentin

A series of new 2-(1-(aminomethyl)cyclohexyl)acetic acid derivatives, 4a-j was synthesized and their biological activity was determined. The chemical structures were confirmed by elemental analyses, UV-visible, FT-IR and 1H NMR spectral studies. The structure-activity relationship for antioxidant activity was discussed. Most of the new compounds showed DPPH radical scavenging activity, where compounds 4f, 4d and 4e were the best radical scavengers.

Autorentext

I Dr. L. Mallesha, completed Ph.D.in Chemistry from University of Mysore, Mysuru. I joined as an Asst. Professor in PG Dept. of Chemistry at JSS College of Arts, Commerce and Science, Mysuru.I have published more than 50 research papers.I have served as reviewer & editorial board member in 3 journals.I am guiding 01 Ph.D. Student under UOM,Mysuru.