Immunogenetics of Fungal Diseases

This book provides up-to-date information on immunogenetics of fungal diseases in the context of primary and acquired immunodeficiencies. Different aspects of this emerging field are covered, including epidemiology of fungal diseases, innate and adaptive antifungal immunity, and the role of immunogenetics in defining susceptibility to fungal diseases in primary (CMC, CGD, etc.) immunodeficiencies and hematologic patients. The available information will also be discussed in the scope of new biomarker discovery and development of immunotherapeutic approaches for personalized diagnostics and therapy. The book addresses Professors, researchers and advanced students of Medicine, Immunology, Microbiology and Genetics.

Maximizes readers' insight into immunology of common and emerging fungal diseases Provides fundamental insights into approaches for personalized therapy Presents genetic tools to define the susceptibility to fungal diseases

Autorentext
Agostinho Carvalho, University of Minho, Life and Health Sciences Research Institute (ICVS), School of Medicine, Campus de Gualtar, 4710-057 Braga, Portugal.

Inhalt

Chapter 1 - Fungal Infections in Primary and Acquired Immunodeficiencies.- Chapter 2 Immunity to Fungal Infections.- Chapter 3 - Genetics of Chronic Mucocutaneous Candidiasis.- Chapter 4 - Chronic Granulomatous Disease and Aspergillosis.- Chapter 5 - Primary Immunodeficiencies and Dermatophytosis.- Chapter 6 - Genetic Determinants of Host Susceptibility to Fungal Diseases in Solid Organ Transplantation and Hematological Patients.- Chapter 7 - Immunogenetics of Chronic and Allergic Aspergillosis.- Chapter 8 - Biomarker Applications in Diagnostics of Fungal Infections.- Chapter 9 - Immunotherapy of Invasive Fungal Disease.- Chapter 10 - Vaccination against fungal diseases: lessons from Candida albicans.