IMMUNOLOGY OF ORAL CANCER

Cancer-related inflammation has emerged as one of the hallmarks of cancer. The effect of inflammation on most cancers is two-edged, with cancer also affecting the process of inflammation. Various factors plays a crucial role in tumor suppression such as TLR-2, Mast cells, tumor infiltrating lymphocytes (TILs) and tumor-associated macrophages. Viral-associated HNSCC has become a significant global burden. Rapid advances in the field of immuno-oncology and the constantly growing knowledge of the immunosuppressive mechanisms and effects of tumor cancer have allowed for the use of effective and personalized immunotherapy as a first-line therapeutic procedure or an essential component of a combination therapy for primary, relapsed and metastatic HNSCC. Immunological typing of tumour should be considered with decisive role in diagnostic and prognostic pathology in future.

Autorentext

Assistenzarzt am Shree Bankey Bihari Dental College and Research Centre, Ghaziabad, INDIEN.