IMPACT OF ADANSONIA DIGITATA LEAVES EXTRACT

Fourty two adult Wistar rats 7-8 weeks old weighing about 160-200 gram wererandomly assigned into six experimental groups comprising of five Wistar rats ineach group: Group 1 (control) received distilled water (1ml/rat) orally. Group 2 (IND50mg/kg) fasted for 48 h before intraperitoneal injection of indomethacin. Group 3(100mg/kg CMD+50mg/kg IND) received cimetidine (100mg/kg) orally for twoweeks. Group 4 (100mg/kg AD+50mg/kg IND) received aqueous extract of A.digitata l. leaves (100mg/kg) daily for two weeks orally. Group 5 (150mg/kg AD+50mg/kg IND) received aqueous extract of A. digitata l. leaves (150mg/kg) daily fortwo weeks orally. Group 6 (200 mg/kg AD+50mg/kg IND) received aqueous extractof A. digitata l. leaves (200mg/kg) daily for two weeks orally. Indomethacin,cimetidine and all the extract treated groups were fasted for 48 h beforeintraperitoneal injection of indomethacin (50mg/kg) for ulcer induction.

Autorentext

Aliyu Abdullahi Isyaku born in Kano state Nigeria. He obtained BSc (Hons) in Human physiology at Ahmadu Bello University Zaria in 2015 and MSc in Human physiology at Bayero University Kano in 2023. Currently he is an academic instructor (lecturer) at Maryam Abacha American University of Nigeria, Kano.