Infectious Disease in Aquaculture

With an ever increasing demand for seafood that cannot be met by capture fisheries alone, growing pressure is being placed on aquaculture production. However, infectious diseases are a major constraint. Infectious disease in aquaculture: prevention and control brings together a wealth of recent research on this problem and its effective management.

Part one considers the innate and adaptive immune responses seen in fish and shellfish together with the implications of these responses for disease control. The specific immune response of molluscs and crustaceans is considered in depth, along with the role of stress in resistance to infection. Advances in disease diagnostics, veterinary drugs and vaccines are discussed in part two, with quality assurance, the use and effects of antibiotics and anti-parasitic drugs in aquaculture, and developments in vaccination against fish are explored. Part three focuses on the development of specific pathogen-free populations and novel approaches for disease control. Specific pathogen free shrimp stocks, developments in genomics and the use of bacteria and bacteriophages as biological agents for disease control are explored, before the management and use of natural antimicrobial compounds.

With its distinguished editor and expert team of contributors, Infectious disease in aquaculture: prevention and control provides managers of aquaculture facilities and scientists working on disease in aquaculture with a comprehensive and systematic overview of essential research in the prevention and control of infectious disease.

Autorentext
Brian Austin is the Director of the Institute of Aquaculture and Professor of Microbiology at the University of Stirling. He is internationally-known for his research on infectious disease in aquaculture.

Inhalt

Contributor contact details

Woodhead Publishing Series in Food Science, Technology and Nutrition

Preface

Part I: Immune responses in fish and shellfish and their implications for disease control

Chapter 1: The innate and adaptive immune system of fish

Abstract:

1.1 Introduction

1.2 Overview of immune cells and organs in fish

1.3 Fish innate immune response

1.4 An overview of the adaptive immune response in fish

1.5 Immune regulation: the cytokine network in fish

1.6 Conclusions

Chapter 2: Crustacean immune responses and their implications for disease control

Abstract:

2.1 Introduction

2.2 Cellular defence

2.3 Hematopoiesis

2.4 Defence against viruses

2.5 Pattern recognition in crustaceans

2.6 The prophenoloxidase (proPO) cascade

2.7 Coagulation

2.8 Antimicrobial proteins

2.9 Future trends and conclusions

Chapter 3: Immune responses in molluscs and their implications for disease control

Abstract:

3.1 Introduction

3.2 The molluscan immune system

3.3 Disease control in bivalves

3.4 Conclusions

3.5 Acknowledgements

Chapter 4: Stress and resistance to infectious diseases in fish

Abstract:

4.1 Introduction: disease is not just the presence of pathogens

4.2 Fish immune and stress responses

4.3 Individual variability and population level effects

4.4 Conclusions

Part II: Advances in disease diagnostics, veterinary drugs and vaccines

Chapter 5: Advances in diagnostic methods for mollusc, crustacean and finfish diseases

Abstract:

5.1 Introduction

5.2 Mollusc disease diagnostic methods

5.3 Crustacean disease diagnostic methods

5.4 Finfish disease diagnostic methods

5.5 Future trends

Chapter 6: Quality assurance in aquatic disease diagnostics

Abstract:

6.1 Introduction

6.2 The importance of valid and reliable aquatic disease diagnosis and the role of quality assurance systems

6.3 Sampling submission and handling for aquatic disease diagnosis

6.4 The importance of assay performance in aquatic disease diagnosis

6.5 Validation of quality assurance systems for aquatic diagnostic facilities

6.6 Interpreting and reporting results under a quality assurance system

6.7 Accreditation and auditing of disease diagnostic laboratories

6.8 Conclusions

Chapter 7: Antibiotics in aquaculture: reducing their use and maintaining their efficacy

Abstract:

7.1 Introduction

7.2 The epidemiology and aetiology of bacterial diseases in aquatic animals

7.3 The use of antibiotics in aquaculture

7.4 Efficacy of antimicrobial therapy in aquaculture

7.5 Laboratory detection of clinical resistance

7.6 The Clinical and Laboratory Science Institute (CLSI) approach to susceptibility testing in aquaculture

7.7 Questions concerning the CLSI approach

7.8 Future trends: the way forward for susceptibility testing

7.9 Conclusions

7.10 Acknowledgements

Chapter 8: Considerations for the use of anti-parasitic drugs in aquaculture

Abstract:

8.1 Introduction

8.2 Factors in successful treatment with anti-parasitic drugs

8.3 Trigger points for treatment with anti-parasitic drugs in aquaculture

8.4 Future trends

Chapter 9: Developments in vaccination against fish bacterial disease

Abstract:

9.1 Introduction

9.2 Methods of administration of vaccines for fish

9.3 Determination of effectiveness of the vaccines

9.4 Vaccine composition

9.5 Mode of action of vaccines

9.6 Conclusions

Chapter 10: Developments in adjuvants for fish vaccines

Abstract:

10.1 Introduction

10.2 Fish immune responses: implications for the developm