Inflammatory Breast Cancer: An Update

Inflammatory breast cancer is the most deadly subtype of breast cancer. Although its molecular characteristics have yet to be established, this book summarizes current molecular and mechanistic findings, which may lead to new diagnostic tools and therapies.

Inflammatory breast cancer is the most deadly subtype of breast cancer because it can spread to other organs despite of multidisciplinary approach. However, the molecular characteristic of this aggressive disease is yet to be established. This book is the one of the few textbooks that summarizes the latest information dated to inflammatory breast cancer. The uniqueness of this book is that it has summarized the latest molecular and mechanistic findings, which may lead to novel diagnostic tool or therapeutic approach to fight this deadly disease.

The latest research of inflammatory breast cancer The latest management of inflammatory breast cancer Secret of the most aggressive breast cancer revealed How rare cancer can be tackled in a comprehensive manner Excellent model for studying breast cancer metastasis

Inhalt

Introduction: Why IBC Now.-1. Epidemiology.-2 Diagnosis, Criteria and Controversy.-3 IBC Registration Study.-4 Pathology: Histomorphometrical Features Of IBC: Angiogenesis, Lymphangiogenesis, and Tumor Emboli.-5 Staging and Imaging.-6 Surgery.-7 Radiation Therapy.-8 Systemic Therapies.-9 Metastatic Treatment by Chemotherapy.-10 Role of Multidisciplinary Team Formation.-11 Role of High-Dose Chemotherapy.-12 Cell Line and Animal Models.-13 Signal Pathway in IBC.-14 Molecules That Drives the Metastasis and Invasion.-15 Inflammation.-16 Immunological Changes.-17 Angiogenesis and Lymphoangiogenesis.-18 Microarray Analysis Identifies a Peculiar IBC Expression Signature.-19 Stem Cell Gene Expression Signature in IBC.-20 The Effect of Systemic Chemotherapy on Minimal Residual Disease in The Blood And Bone Marrow Of Patients With IBC.-21 Patient's Perspective.- Index.