Information Thermodynamics on Causal Networks and Its Application to Biochemical Signal Transduction

In this book the author presents a general formalism of nonequilibrium thermodynamics with complex information flows induced by interactions among multiple fluctuating systems.
The author has generalized stochastic thermodynamics with information by using a graphical theory. Characterizing nonequilibrium dynamics by causal networks, he has obtained a novel generalization of the second law of thermodynamics with information that is applicable to quite a broad class of stochastic dynamics such as information transfer between multiple Brownian particles, an autonomous biochemical reaction, and complex dynamics with a time-delayed feedback control. This study can produce further progress in the study of Maxwell's demon for special cases.
As an application to these results, information transmission and thermodynamic dissipation in biochemical signal transduction are discussed. The findings presented here can open up a novel biophysical approach to understanding information processing in living systems.

Nominated as an outstanding contribution by the University of Tokyo's Physics Department in 2015 Presents studies of a novel generalization of the second law of thermodynamics for small subsystems on causal networks Focusses on stochastic thermodynamics with information applicable to a broad class of nonequilibrium dynamics such as biochemical signal transduction Includes supplementary material: sn.pub/extras

Autorentext

Dr. Sosuke Ito

Department of Physics, The University of Tokyo

Inhalt

Introduction to Information Thermodynamics on Causal Networks.- Review of Classical Information Theory.- Stochastic Thermodynamics for Small System.- Information Thermodynamics under Feedback Control.- Bayesian Networks and Causal Networks.- Information Thermodynamics on Causal Networks.- Application to Biochemical Signal Transduction.- Information Thermodynamics as Stochastic Thermodynamics for Small Subsystem.- Further Applications of Information Thermodynamics on Causal Networks.- Conclusions.