Long-Term Potentiation

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In neuroscience, long-term potentiation (LTP) is a long-lasting enhancement in signal transmission between two neurons that results from stimulating them synchronously. It is one of several phenomena underlying synaptic plasticity, the ability of chemical synapses to change their strength. As memories are thought to be encoded by modification of synaptic strength, LTP is widely considered one of the major cellular mechanisms that underlies learning and memory. LTP shares many features with long-term memory, making it an attractive candidate for a cellular mechanism of learning. For example, LTP and long-term memory are triggered rapidly, each depends upon the synthesis of new proteins, each has properties of associativity, and each can last for many months. LTP may account for many types of learning, from the relatively simple classical conditioning present in all animals, to the more complex, higher-level cognition observed in humans. At a cellular level, LTP enhances synaptic transmission. It improves the ability of two neurons, one presynaptic and the other postsynaptic, to communicate with one another across a synapse.

Weitere Informationen

  • Allgemeine Informationen
    • GTIN 09786130269555
    • Editor Frederic P. Miller, Agnes F. Vandome, John McBrewster
    • Sprache Englisch
    • Größe H220mm x B150mm x T8mm
    • Jahr 2009
    • EAN 9786130269555
    • Format Fachbuch
    • ISBN 978-613-0-26955-5
    • Titel Long-Term Potentiation
    • Untertitel Neuroscience, Neuron, Chemical synapse, Learning, Long-term memory, Protein biosynthesis, Neurotransmission, Cognition, Neurotransmitter, Neurotransmitter receptor, Hippocampus, Alzheimer's disease
    • Gewicht 227g
    • Herausgeber Alphascript Publishing
    • Anzahl Seiten 140
    • Genre Biologie

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