Magnetic Nanotubes as Magnetic Resonance Contrast Agents

An increasing interest in medical application of
nanotechnology has heightened the need for synthesis
of nanoparticles with well-defined dimensions and
multifunctionalities. Based on template synthesis
method, magnetic nanotubes (MNT) were successfully
prepared with precise morphology control. The MNTs
have super magnetic properties, including high
saturation magnetization and magnetic resonance
relaxivities. Cytotoxicity and cellular uptake of
SNTs were investigated for primary and cancer cells.
The nanotubes showed limited toxicity which was
concentration-, surface charge-, and length-
dependent. The internalization was confirmed with
both confocal microscopy and TEM studies. These
studies were directed by Professor Sang Bok Lee.

Autorentext

Dr Xia Bai is a staff scientist at Pixelligent LLC doing nanocrystal synthesis, modification and characterization. She recievied PhD in Chemistry at University of Maryland(2008), MS in Applied Science(2005)at University of Delaware(2005), and MS in Material Science & Engineering at University of Science and Technology Beijing(2002).

Klappentext

An increasing interest in medical application of nanotechnology has heightened the need for synthesis of nanoparticles with well-defined dimensions and multifunctionalities. Based on template synthesis method, magnetic nanotubes (MNT) were successfully prepared with precise morphology control. The MNTs have super magnetic properties, including high saturation magnetization and magnetic resonance relaxivities. Cytotoxicity and cellular uptake of SNTs were investigated for primary and cancer cells. The nanotubes showed limited toxicity which was concentration-, surface charge-, and length- dependent. The internalization was confirmed with both confocal microscopy and TEM studies. These studies were directed by Professor Sang Bok Lee.