Management of abdominal thrombosis in non-cirrhotic patients:

The objective of this work was to describe the profile of non-cirrhotic patients with abdominal thrombosis for whom the search for thrombophilia was indicated and to determine its impact on treatment. This was a retrospective study including 48 patients followed for abdominal thrombosis over a 12-year period. The mean age was 47 years. Portal location was the most frequent (92%). An etiology was identified in 28 patients: mainly local causes (n=14). Congenital thrombophilia was investigated in 33 patients. It was indicated particularly in young subjects (less than 50 years old). A probable constitutional deficiency in coagulation inhibitors was retained in 3 patients. Acquired thrombophilia was related to antiphospholipid antibody syndrome (n=1) and/or hyperhomocysteinemia (n=6). Anticoagulation was indicated in 35 patients. In multivariate analysis, only the totality of the thrombosis was a determining factor in the decision to start treatment. In contrast, no factor was significantly associated with the decision to prolong anticoagulation.

Autorentext

Professor associado em Hematologia Biológica na Faculdade de Medicina de Tunis - Universidade El Manar de Tunis, a trabalhar no Hospital La Rabta - Departamento de Hematologia.