Mandibular Reconstruction With Axial Vascularization

Reconstruction of large and complex bone segments is one of the most challenging problems facing modern clinical practice. In order to diminish the donor site morbidity associated with autogenous bone transfer, synthetic biomaterials are being used nowadays to regenerate lost bone due to disease or trauma. The majority of currently applied regenerative medicine approaches rely on extrinsic vascularization, which could not be applied to reconstruction after cancer ablation. This book presents an experimental pilot study introducing for the first time the concept of axial vascularization of bone substitutes to regenerate mandibular defects in a large animal model (goat). The book is also presenting a review about conventional reconstructive techniques, describes the fine details of a novel model for axial vascularization and discusses its results in comparison with literature. The book contains valuable details suitable for graduate, and post-graduate researchers in the field of Reconstructive Maxillofacial surgery as well as biotechnology and Regenerative medicine.

Autorentext

Ahmad Eweida, MD, MRCS; born on 11.6.1980 in Alexandria, Egypt, received his doctorate degree from the University of Erlangen-Nürnberg in Germany in 2012. Ahmad is an assistant lecturer of Head and Neck Surgery and a senior researcher in the TE labs in the University of Alexandria. His research focuses on vascularization and bone regeneration.