Mass Spectrometry-Based Approaches for Treating Human Diseases and Diagnostics

This book presents the technological advances in the field of mass spectrometry-based approaches for treating human diseases and diagnostics as well as the application of such approaches to study, in depth, human diseases, biomarkers discovery and validation, and to provide mechanistic insights of potential new therapeutics. This is an ideal book for students, technicians, researchers, and medical doctors that work in the field of mass spectrometry and proteomics

Covers recent advances in the technology, characterization of human homeostatis and diseases, and potential treatments Describes metabolomics and lipodomics methods, as well as advances in proteomic methods Highlights mass-spectrometry-based personalized medicine

Autorentext
Dr. Thiago Verano-Braga is an Associate Professor in the Department of Physiology and Biophysics at the Federal University of Minas Gerais (UFMG) in Brazil.

Inhalt
Preface.- Isolation of Extracellular Vesicles Using Titanium Dioxide Microspheres.- Glycosort: a computational solution to post-process quan-titative large-scale intact glycopeptide analyses.- Applications of Mass Spectrometry in the Characterization, Screening, Diagnosis, and Prognosis of COVID-19.- Proteomics and Metabolomics in Congenital Zika Syndrome: A Review of Molecular Insights and Biomarker Discovery.- Mass Spectrometry Applications to Study Human Microbiome.- Neuroproteomics: unveiling the molecular insights of psychiatric disorders with a focus on anxiety disorder and depression.- Proteomic-based studies on memory formation in normal and neurodegenerative diseases affected brains.- Cardioproteomics: insights on cardiovascular diseases.- Kidney Disease and Proteomics: A Recent Overview of a Useful Tool for Improving Early Diagnosis.- Multi-omics investigations in endocrine systems and their clinical implications.- Omics to Unveil Diabetes Mellitus Pathogenesis and Biomarkers: Focus on Proteomics, Lipidomics and Metabolomics.- Proteomics: Unraveling the Crosstalk Between Innate Immunity and Disease Pathophysiology, Diagnostics, and Treatment Options.- Applications of Proteomics in Probiotics having Anticancer and Chemo-preventive Properties.- Mass spectrometry-based characterization of protein aggregates in tissues and biofluids.- Index.