Materials and Devices for Bone Disorders

Materials for Bone Disorders is written by a cross-disciplinary team of research scientists, engineers, and clinicians and bridges the gap between materials science and bone disorders, providing integrated coverage of biomaterials and their applications. The bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders are introduced, as are their interactions with cells, biomolecules, and body tissues. The main types of bone disorder and disease are covered including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders.

Bone disorders are common across all ages. Various forms of bone disorders can change the lifestyle of otherwise normal and healthy people. With the development of novel materials, many forms of bone disorders are becoming manageable, allowing people to lead a fairly normal life. Specific consideration is given to areas where recent advances are enabling new treatments, such as the use of resorbable ceramics in bone tissue engineering and drug delivery, newer polymer-based implants in load-bearing contexts, and engineering biomaterials surfaces including modifying surface chemistry. Ethical and regulatory issues are also explored.

Autorentext
Susmita Bose is a Professor in the School of Mechanical and Materials Engineering, an affiliate professor in the Department of Chemistry at Washington State University (WSU). In 2004, Dr. Bose received the prestigious Presidential Early Career Award for Scientist and Engineers (PECASE, the highest honor given to a young scientist by the US President at the White House) award from the National Science Foundation. Dr. Bose was named as a Kavli fellow” by the National Academy of Sciences. In 2009, she received the prestigious Schwartzwalder-Professional Achievement in Ceramic Engineering (PACE) Award, and in 2014 Richard M. Fulrath Award, which is an international award given to one academician in the US annually (below age 45), from the American Ceramic Society. Dr. Bose is editorial board member for several international journals, including Acta Biomaterialia, Journal of the American Ceramic Society, Journal of Materials Chemistry B, International Journal of Nanomedicine and Additive Manufacturing. Dr. Bose has published over 200 technical papers with ~ 5000 citations, h” index 40. Dr. Bose is a fellow of the American Institute for Medical and Biological Engineering (AIMBE) and the American Ceramic Society (ACerS).Prof. Bandyopadhyay is Herman and Brita Lindholm Endowed Chair Professor at the School of Mechanical and Materials Engineering, Washington State University (WSU), also a Fellow of the National Academy of Inventors (NAI), American Ceramic Society (ACerS), American Society for Materials (ASM International), American Institute for Medical and Biological Engineering (AIMBE) and American Association for the Advancement of Science (AAAS). He has published over 250 technical papers including over 170 journal papers. He holds 11 US patents and several patent applications are currently pending at the United States Patent and Trademark Office. He has edited 8 books.His research expertise lies with additive manufacturing of metallic and ceramic materials and their composites towards structural, bio- and piezoelectric materials.

Klappentext
Materials for Bone Disorders is written by a cross-disciplinary team of research scientists, engineers, and clinicians and bridges the gap between materials science and bone disorders, providing integrated coverage of biomaterials and their applications. The bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders are introduced, as are their interactions with cells, biomolecules, and body tissues. The main types of bone disorder and disease are covered including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders. Bone disorders are common across all ages. Various forms of bone disorders can change the lifestyle of otherwise normal and healthy people. With the development of novel materials, many forms of bone disorders are becoming manageable, allowing people to lead a fairly normal life. Specific consideration is given to areas where recent advances are enabling new treatments, such as the use of resorbable ceramics in bone tissue engineering and drug delivery, newer polymer-based implants in load-bearing contexts, and engineering biomaterials surfaces including modifying surface chemistry. Ethical and regulatory issues are also explored.

Inhalt

1. Introduction to Biomaterials and Devices for Bone Disorders
2. Bone Biology and Effects of Pharmaceutical Intervention on Bone Quality
3. Bone Disorders
4. Implants for Joint Replacement of the Hip and Knee
5. Material and Mechanobiological Considerations for Bone Regeneration
6. Ceramics in Bone Grafts and Coated Implants
7. Ceramic Coatings in Load-Bearing Articulating Joint Implants
8. Polymers and Composites for Orthopedic Applications
9. Surface Modifications and Surface Characterization of Biomaterials Used in Bone Healing
10. Predictive Methodologies for Design of Bone Tissue Engineering Scaffolds
11. Ethical Issues in Biomaterials Research
12. Research on Bone Disorders-From Ideas to Clinical Use Product-The Path to Commercialization
13. Current Challenges and Future Needs in Biomaterials and Devices for Bone Disorders