MEMS-based Transdermal Drug Delivery

This book introduces transdermal drug delivery and developments in transdermal drug delivery techniques including system level design approach of a novel miniaturized medical device to offer precise and painless drug delivery via a skin-based transdermal route. It discusses the MEMS- based fabrication technique and related aspects.

This book introduces transdermal drug delivery and the developments that have taken place in various transdermal drug delivery techniques including the system-level design approach of a novel miniaturized medical device to offer precise and painless drug delivery via a skin-based transdermal route. It discusses the microelectromechanical systems (MEMS)-based fabrication technique and the design, fabrication and characterization of different MEMS-based components like microneedles and micropumps. It further includes a MEMS-based component micropump with design, analysis, fabrication and characterization of the transdermal drug delivery device and challenges encountered in the design improvements.

Features:

• Summarizes transdermal drug delivery systems especially with a focus on MEMS and microneedles, including theoretical concepts
• Emphasizes system integration by describing simulation and design techniques as well as experimental fabrication
• Discusses system-level integration for miniaturized therapeutic devices
• Includes working simulation models covering microneedles and micropump analysis

• Explores future direction in development of pertinent devices The book is aimed at researchers, professionals, and graduate students in biomedical engineering, microelectronics, micro-electro-mechanical-systems, and drug delivery.

  Autorentext

  Richa Mishra is an Assistant Professor in Electronics and Communication Engineering Department, Birla Institute of Technology (BIT), Mesra, India.

Tarun Kanti Bhattacharyya holds the prestigious position of Institute Chair Professor at IIT Kharagpur.

Inhalt

1 Transdermal Drug Delivery Systems. 2 At the bottom - Microfluidics and Scaling Laws. 3 Microneedles - New tools of painless interface to skin. 4 Miniaturization using microfabrication techniques. 5 Design and simulation of microneedles. 6 Fabrication and characterization of hollow Polymer microneedles. 7 C-MEMS process-based post fabrication and strength enhancement of microneedles. 8 Micropumps for drug delivery. 9 Piezoelectric Actuator-based Micropumps. 10 Ionic Polymer Metal Composite Actuators for micropumps. 11 Microneedle and IPMC micropump integrated drug delivery system