Methods of Organic Synthesis

This textbook covers the most important modern and classic synthetic methods/named reactions and illustrates which substrates they can be most efficiently applied to. Based on commonly used functionalities or typical reaction types, the reader is gradually provided with the necessary tools to either understand a published synthesis or to aid in planning their own synthetic approach.

· Assessment and comparison of the most important synthetic methods, including comprehensive literature references

· Detailed explanations of the involved mechanisms

· Numerous examples of their application in complex syntheses

· Tools for the design and optimization of synthesis approaches in both an academic and industrial context

Notable emphasis is placed on understanding the respective reaction mechanisms. This allows for the comprehension and prediction of the selectivity of a transformation and its compatibility with common functional groups. New developments beyond the provided scope can accordingly be understood based on the covered content.

The strategic use of color in the figures enables the reader to internalize and intuitively grasp the material. Potential users are also provided with guidelines and summary tables to make it easier to get started in practice.

Enables readers to gain an overview of various methods of organic synthesis Presents detailed explanation of the reaction mechanisms Is particularly suitable for Master's students and doctoral candidates

Autorentext

Alexander Düfert completed his doctorate in organic synthesis at the University of Göttingen. After a PostDoc in homogeneous catalysis at the Massachusetts Institute of Technology, he has held various positions at BASF since 2013. Since 2019, he has also been teaching industrial organic synthesis at Saarland University.

Inhalt

1.Stereoelectronic effects.- 2.Carbonyl Chemistry.- 3.Synthsis and Derivatization of Alkens and Alkynes.- 4.Oxidation and Reduction.- 5.Pericyclic Reactions.- 6.Transition Metal-Catalysed Coupling Reactions.- 7.Metathesis.- 8.Organocatalysis.- 9.Click Reactions.- 10.Modern Radical and Redox Chemistry.- 11.Principles of Synthesis Planning.